Astragin - The Absorption Assistant
AstraGin is consistent and effective product based of traditional Chinese medicine where these two herbs were associated with the Spleen Meridian and it's “Chi” which is the energy of the spleen in relation to how the spleen then affects and governs digestion, immunity, mucosal integrity and inflammation responses, absorption, and movement of fluids. Modern science has now proven this to be true in how these herbs interact with the body, how did they know this all that time ago!?
The Results
Astragin has been shown to be most effective in the absorption of nutrients from our diet. This is done via the mRNA and transporter protein expression. It's assistance with amino acid absorption and their efficacy in the body. So much so that it was shown to improve the absorption percentage of the following amino acids and other vital nutrients:Astragin is also known for its benefits in aiding:
- Regulation of appetite.
- Gut health, immune support, and nutrition profile of microbiome.
- Increase in the function of Protein Synthesis.
Black pepper for absorption?
In recent years we have seen a huge trend spike in the use of black pepper aiding in the absorption of nutrients into the body. With that the debate on how it does this if its the most effective method and what actually makes it more effective than having said nutrient on its own?Black Pepper and curcumin, for example, this is a huge trend. You simply can't utilize the maximum benefits of turmeric/curcumin without pairing it with black pepper... apparently. That's where the industry has it a little bit back to front. Black pepper does in fact enhance absorption, but at a compromise to the body. It damages the mucosal integrity, inhibits the scavenging of free radicals and also inhibits phase 1 metabolism of the liver. In fact, p450 pathways are inhibited so that the saturation can occur.
This study which we will reference below showed that black pepper is a potent drug metabolism inhibitor Oral administration of piperine in rats strongly inhibited the hepatic AHH and UDP-glucuronyl transferase activities. This is why we left it out of our products, we want to enhance glucuronidation for things like xenoestrogen and xenobiotics.
How does Astragin compare?
Astragin enhances absorption of nutrients by improving the mucosal integrity rather than damaging it and enhancement of mRNA and transporter protein expression. Allowing more specific nutrients to be absorbed through the small intestine to be transported to the bloodstream to be readily available to the 37 trillion cells in the human body. No compromise to the body, its detoxification abilities or antioxidant response mechanisms.Astragin improved overall absorption of cucurumin by 92% in 2 hours without affecting any phase 1 liver metabolism actions. Its quite an amazing product!
References:
1. S.A.Adibi, et al. The kinetics of amino acid absorption
and alteration of plasma composition of free amino
acids after intestinal perfusion of amino acid mixture. The
American Journal of Clinical Nutrition, 1967, Vol. 20, No.1,
Jan., p.24-33.
2. P.J. Reeds. The gut and amino acid homeostasis.
Nutrition, 2000, Vol. 16, No. 7/8, p,666-668.
3. Z.Q. Hei, et al. Protective effect of Astragalus
membranaceus on intestinal mucosa reperfusion injury
after hemorrhagic shock in rats. World Journal of Gastroenterology.
2005, Vol. 11(32), p.4986-4991.
4. G.A.M. Ten Have, et al. Absorption Kinetics of
Amino Acids, Peptides and Intact proteins. International
Journal of Sports Nutrition and Exercise Metabolism. 2007,
17, S23-S36.
5. T.C. Chang, et al. Effect of Ginsenosides on
Glucose Uptake in Human Caco-2 Cells Is Mediated
through Altered Na+/Glucose Cotransporter 1 Expression.
J. Agric. Food Chem. 2007, vol. 55, p.1993-1998.
6. S.F. Huang, et al. Effect of Ginsenoside Rb1 on
Glucose Uptake and Expression of Glucose Transporters in
Animal Cells. Adaptation Biology and Medicine. 2011, vol.
6, p.447-460.